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Additional bedtime H2-receptor antagonist for the control of nocturnal gastric acid breakthrough (Cochrane Review) ABSTRACT Background: Nocturnal gastric acid breakthrough(NAB) is defined as intragastric pH<4 for more than one continuous hour overnight. Adding H2-receptor antagonists (H2RAs)at bedtime to high-dose proton pump inhibitors is likely to enhance nocturnal gastric pH contr . . . |
Full article: The full article is available on Wiley InterScience at http://www.thecochranelibrary.com |