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Natalizumab for induction of remission in Crohn's disease (Cochrane Review) ABSTRACT Background: The pathogenesis of Crohn's disease involves migration of leukocytes into gut tissue and subsequent inflammation. Natalizumab (TysabriŽ, Elan Pharmaceuticals and Biogen Idec) a recombinant humanized IgG4 monoclonal antibody that blocks adhesion and s . . . |
Full article: The full article is available on Wiley InterScience at http://www.thecochranelibrary.com |