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Methotrexate for treating rheumatoid arthritis (Cochrane Review) ABSTRACT Background: Methotrexate (MTX) is a folic acid antagonist widely used for the treatment of neoplastic disorders. MTX inhibits the synthesis of deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and proteins by binding to dihydrofolate reductase. Currently, MTX . . . |
Full article: The full article is available on Wiley InterScience at http://www.thecochranelibrary.com |