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Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis (Cochrane Review) ABSTRACT Background: Methotrexate (MTX) is classified pharmacologically as an antimetabolite due to its antagonistic effect on folic acid metabolism. Although its mechanism of action is uncertain, it has become the second line drug of choice for many rheumatologists |
Full article: The full article is available on Wiley InterScience at http://www.thecochranelibrary.com |